The UK HIV Drug Resistance Database is a central repository for resistance tests performed as part of routine clinical care throughout the UK. Established in 2001, by the end of 2016 over 135,000 test results, most in the form of viral gene sequences, had been received and curated.

UK HIV Drug Resistance Database

HIV drug resistance

A major area of research activity by the database is the national surveillance of HIV-1 drug resistance, tracking changes in its prevalence over time. Analyses are done separately for drug-naïve patients to monitor transmitted drug resistance (TDR), and drug-experienced patients to monitor the extent of resistance by drug class and prevalence of multi-class resistance.

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